Question Details:

Wirelss mouse stopped working, put in new batteries, no help, bought new mouse, no help, changed usb ports, still not working. Running window xp

Answer:

A mouse may not be detected in Windows because of any of the below possibilities:

1. Mouse conflict
2. Not connected properly
3. Mouse software or driver conflict
4. Computer frozen
5. Bad Mouse

From what you suggested it could be a conflict or your USB ports are not working correctly.

More details here.